Week 3 
Week 3 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 9/18 | 17:15 | MIA | BUF | Highmark Stadium  | Prime | |
| Su | 9/21 | 10:00 | ATL | CAR | Bank of America Stadium | FOX | |
| Su | 9/21 | 10:00 | GB | CLE | Huntington Bank Field | FOX | |
| Su | 9/21 | 10:00 | HOU | JAX | EverBank Stadium | CBS | |
| Su | 9/21 | 10:00 | CIN | MIN | U.S. Bank Stadium | CBS | |
| Su | 9/21 | 10:00 | PIT | NE | Gillette Stadium | CBS | |
| Su | 9/21 | 10:00 | LAR | PHI | Lincoln Financial Field | FOX | |
| Su | 9/21 | 10:00 | NYJ | TB | Raymond James Stadium | FOX | |
| Su | 9/21 | 10:00 | IND | TEN | Nissan Stadium | CBS | |
| Su | 9/21 | 10:00 | LV | WAS | Northwest Stadium | FOX | |
| Su | 9/21 | 13:05 | NO | SEA | Lumen Field | CBS | |
| Su | 9/21 | 13:05 | DEN | LAC | SoFi Stadium | CBS | |
| Su | 9/21 | 13:25 | DAL | CHI | Soldier Field II | FOX | |
| Su | 9/21 | 13:25 | ARI | SF | Levi's Stadium | FOX | |
| Su | 9/21 | 17:20 | KC | NYG | MetLife Stadium | NBC | |
| Mo | 9/22 | 17:15 | DET | BAL | M&T Bank Stadium | ABC | |