Week 2 
Week 2 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 9/11 | 17:15 | WAS | GB | Lambeau Field  | Prime | |
| Su | 9/14 | 10:00 | CLE | BAL | M&T Bank Stadium | CBS | |
| Su | 9/14 | 10:00 | JAX | CIN | Paycor Stadium | CBS | |
| Su | 9/14 | 10:00 | NYG | DAL | AT&T Stadium | FOX | |
| Su | 9/14 | 10:00 | CHI | DET | Ford Field | FOX | |
| Su | 9/14 | 10:00 | NE | MIA | Hard Rock Stadium | CBS | |
| Su | 9/14 | 10:00 | SF | NO | Caesars Superdome | FOX | |
| Su | 9/14 | 10:00 | BUF | NYJ | MetLife Stadium | CBS | |
| Su | 9/14 | 10:00 | SEA | PIT | Acrisure Stadium | FOX | |
| Su | 9/14 | 10:00 | LAR | TEN | Nissan Stadium | CBS | |
| Su | 9/14 | 13:05 | CAR | ARI | State Farm Stadium | CBS | |
| Su | 9/14 | 13:05 | DEN | IND | Lucas Oil Stadium | CBS | |
| Su | 9/14 | 13:25 | PHI | KC | GEHA Field at Arrowhead Stadium | FOX | |
| Su | 9/14 | 17:20 | ATL | MIN | U.S. Bank Stadium | NBC | |
| Mo | 9/15 | 16:00 | TB | HOU | NRG Stadium | ABC | |
| Mo | 9/15 | 19:00 | LAC | LV | Allegiant Stadium | ESPN | |