Week 6 
Week 6 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 10/15 | 17:15 | SEA | DEN | Empower Field at Mile High  | Prime Video | |
| Su | 10/18 | 6:30 | HOU | JAX | Wembley Stadium | NFL Net | |
| Su | 10/18 | 10:00 | CHI | ATL | Mercedes-Benz Stadium | FOX | |
| Su | 10/18 | 10:00 | BAL | CLE | Huntington Bank Field | FOX | |
| Su | 10/18 | 10:00 | TEN | IND | Lucas Oil Stadium | FOX | |
| Su | 10/18 | 10:00 | NYJ | NE | Gillette Stadium | CBS | |
| Su | 10/18 | 10:00 | NO | NYG | MetLife Stadium | FOX | |
| Su | 10/18 | 10:00 | CAR | PHI | Lincoln Financial Field | CBS | |
| Su | 10/18 | 10:00 | PIT | TB | Raymond James Stadium | CBS | |
| Su | 10/18 | 13:05 | ARI | LAR | SoFi Stadium | FOX | |
| Su | 10/18 | 13:25 | LAC | KC | GEHA Field at Arrowhead Stadium | CBS | |
| Su | 10/18 | 13:25 | BUF | LV | Allegiant Stadium | CBS | |
| Su | 10/18 | 17:20 | DAL | GB | Lambeau Field | NBC | |
| Mo | 10/19 | 17:15 | WAS | SF | Levi's Stadium | ESPN | |