Week 6 
Week 6 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 10/9 | 17:15 | PHI | NYG | MetLife Stadium  | Prime | |
| Su | 10/12 | 6:30 | DEN | NYJ | Tottenham Hotspur Stadium | NFL Net | |
| Su | 10/12 | 10:00 | LAR | BAL | M&T Bank Stadium | FOX | |
| Su | 10/12 | 10:00 | DAL | CAR | Bank of America Stadium | FOX | |
| Su | 10/12 | 10:00 | ARI | IND | Lucas Oil Stadium | FOX | |
| Su | 10/12 | 10:00 | SEA | JAX | EverBank Stadium | FOX | |
| Su | 10/12 | 10:00 | LAC | MIA | Hard Rock Stadium | CBS | |
| Su | 10/12 | 10:00 | NE | NO | Caesars Superdome | CBS | |
| Su | 10/12 | 10:00 | CLE | PIT | Acrisure Stadium | CBS | |
| Su | 10/12 | 13:05 | TEN | LV | Allegiant Stadium | FOX | |
| Su | 10/12 | 13:25 | CIN | GB | Lambeau Field | CBS | |
| Su | 10/12 | 13:25 | SF | TB | Raymond James Stadium | CBS | |
| Su | 10/12 | 17:20 | DET | KC | GEHA Field at Arrowhead Stadium | NBC | |
| Mo | 10/13 | 16:15 | BUF | ATL | Mercedes-Benz Stadium | ESPN | |
| Mo | 10/13 | 17:15 | CHI | WAS | Northwest Stadium | ABC | |