Week 16 
Week 16 | Start (PT) | Visitor | Home | Stadium | TV | |||
| Th | 12/24 | 17:15 | HOU | PHI | Lincoln Financial Field  | Prime Video | |
| Fr | 12/25 | 10:00 | GB | CHI | Soldier Field II | Netflix | |
| Fr | 12/25 | 13:30 | BUF | DEN | Empower Field at Mile High | Netflix | |
| Fr | 12/25 | 17:15 | LAR | SEA | Lumen Field | FOX | |
| Su | 12/27 | 10:00 | TB | ATL | Mercedes-Benz Stadium | TBD | |
| Su | 12/27 | 10:00 | CLE | BAL | M&T Bank Stadium | CBS | |
| Su | 12/27 | 10:00 | CIN | IND | Lucas Oil Stadium | TBD | |
| Su | 12/27 | 10:00 | LAC | MIA | Hard Rock Stadium | FOX | |
| Su | 12/27 | 10:00 | WAS | MIN | U.S. Bank Stadium | TBD | |
| Su | 12/27 | 10:00 | ARI | NO | Caesars Superdome | FOX | |
| Su | 12/27 | 10:00 | NE | NYJ | MetLife Stadium | CBS | |
| Su | 12/27 | 10:00 | CAR | PIT | Acrisure Stadium | TBD | |
| Su | 12/27 | 13:05 | TEN | LV | Allegiant Stadium | FOX | |
| Su | 12/27 | 13:25 | SF | KC | GEHA Field at Arrowhead Stadium | CBS | |
| Su | 12/27 | 17:20 | JAX | DAL | AT&T Stadium | NBC | |
| Mo | 12/28 | 17:15 | NYG | DET | Ford Field | ESPN | |