Week 12 
Week 12 | Start (PT) | Visitor | Home | Stadium | TV | |||
| We | 11/25 | 17:00 | GB | LAR | SoFi Stadium  | Netflix | |
| Th | 11/26 | 10:00 | CHI | DET | Ford Field | CBS | |
| Th | 11/26 | 13:30 | PHI | DAL | AT&T Stadium | FOX | |
| Th | 11/26 | 17:20 | KC | BUF | New Highmark Stadium | NBC | |
| Fr | 11/27 | 12:00 | DEN | PIT | Acrisure Stadium | Prime Video | |
| Su | 11/29 | 10:00 | NO | CIN | Paycor Stadium | CBS | |
| Su | 11/29 | 10:00 | LV | CLE | Huntington Bank Field | FOX | |
| Su | 11/29 | 10:00 | BAL | HOU | NRG Stadium | CBS | |
| Su | 11/29 | 10:00 | NYG | IND | Lucas Oil Stadium | FOX | |
| Su | 11/29 | 10:00 | NYJ | MIA | Hard Rock Stadium | CBS | |
| Su | 11/29 | 10:00 | ATL | MIN | U.S. Bank Stadium | FOX | |
| Su | 11/29 | 13:05 | TEN | JAX | EverBank Stadium | CBS | |
| Su | 11/29 | 13:25 | WAS | ARI | State Farm Stadium | FOX | |
| Su | 11/29 | 13:25 | SEA | SF | Levi's Stadium | FOX | |
| Su | 11/29 | 17:20 | NE | LAC | SoFi Stadium | NBC | |
| Mo | 11/30 | 17:15 | CAR | TB | Raymond James Stadium | ESPN | |